Cerebral Mucormycosis Mimicking a Brain Tumor-Juniper Publishers

JUNIPER PUBLISHERS- OPEN ACCESS JOURNAL OF CASE STUDIES

 Cerebral Mucormycosis Mimicking a Brain Tumor

 Authored by Yin Liu

  

Abstract

We describe a case of intracranial mucormycosis in an immunocompetent child with perfusion features mimicking a brain tumor. Saksenaea species has previously been reported in immunocompetent patients. The source of the infection in our patient was unknown. On brain MRI, the unusual curvilinear and nodular enhancement pattern may reflect the angioinvasive nature of the organism, not previously reported. The finding of increased CBV is typically associated with neoplasms, with CNS infections typically demonstrating decreased CBV. This case demonstrates that fungal infection may present with increased CBV.

Case Report

4-year-old healthy male presented to the emergency room with intractable vomiting, worsening right frontal headaches for one month, and drowsiness for one day. Head CT demonstrated an ill-defined hyperdense right frontal lobe lesion (Figure 1). MRI showed an irregularly enhancing right frontal lobe lesion which extended to the corpus callosum. Subtle associated diffusion restriction was noted with increased cerebral blood volume (Figure 2). A high-grade, hypercellular tumor was suspected, although the enhancement pattern was unusual. A generous brain biopsy was performed with intraoperative pathology revealing granulomatous fungal encephalitis and the lesion was grossly illdefined. Tissue culture confirmed growth of Saksenaea species.

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